Treatment - Generalised anxiety disorder in adults (2024)

Generalised anxiety disorder (GAD) is a long-term condition,but a number of different treatments can help.

If you have other problems alongside GAD, such as depressionor alcohol misuse, these may need to be treated before you have treatment specifically for GAD.

Psychological therapies for GAD

If you have been diagnosed with GAD, you'll usually be advised to try psychological treatment before you're prescribed medication.

You can get talking therapies like cognitive behavioural therapy (CBT) and applied relaxation on the NHS.

You can refer yourself directly to an NHS talking therapies service without a referral from a GP.

Or your GP can refer you if you prefer.

Find an NHS talking therapies service

Guided self-help and cognitive behavioural therapy (CBT)

Your GP or talking therapies service may suggest trying a self-help course to see if it can help you learn to cope with your anxiety.

Self-help courses for GAD are usually based on the principles of cognitive behavioural therapy (CBT).

CBT is a type of talking therapy that can help you manage your problems by changing the way you think and behave.

CBT is one of the most effective treatments for GAD.

There are several ways you may be offered self-help and CBT:

  • you work through a CBT workbook or computer course in your own time
  • you work through a CBT workbook or computer course with the support of a therapist who you see every 1 or 2 weeks
  • you take part in a group course where you and other people with similar problems meet with a therapist every week to learn ways to tackle your anxiety

If these initial treatments don't help, you'll usually be offered more intensive CBT where you usually have weekly sessions with a therapist for 3 to 4 months, or another type of therapy called applied relaxation or medication.

You can try some self-help cognitive behavioural therapy (CBT) techniques on the Every Mind Matters website. This is not a full CBT course or guided self-help, but it has practical self-help tips and strategies based on CBT techniques.

Applied relaxation

Applied relaxation focuses on relaxing your muscles in a particular way during situations that usually cause anxiety.

The technique needs to be taught by a trained therapist andgenerally involves:

  • learning how to relax your muscles
  • learning how to relax your muscles quickly and in response to a trigger, such as the word "relax"
  • practising relaxing your muscles in situations that make you anxious

As with CBT,applied relaxation therapy will usually mean meeting with a therapist for a 1-hour sessionevery week for 3 to 4 months.

Relaxation therapy may not be available in all areas, so you might be offered CBT instead.

Video: Talking therapies for stress, anxiety and depression

Animated video explaining self-referral to talking therapies services for stress, anxiety or depression.

Media last reviewed: 14 March 2022
Media review due: 14 March 2025

Medication

If thepsychological treatments above haven't helped or you'd prefer not to try them, you'll usually be offered medication.

Your GP can prescribe a variety of different types of medication to treat GAD.

Some medication is designed to be taken on a short-term basis, while others are prescribed for longer periods.

Depending on your symptoms, you may need medication to treat your physical symptoms, as well as your psychological ones.

If you're considering taking medication for GAD, your GP should discuss the different options with you in detailbefore you start a course of treatment, including:

  • the different types of medication
  • length of treatment
  • side effects and possible interactions with other medicines
  • which medication is best for you if you’re pregnant, planning a pregnancy or breastfeeding

You should also have regular appointments with your doctor to assess your progress when you're taking medication for GAD.

Thesewill usuallytake place every2 to 4 weeks for the first 3 months, then every 3months after that.

Tellyour GP if you think you may be experiencing side effects from your medication. They may be able to adjust your dose or prescribe an alternative medication.

Selective serotonin reuptake inhibitors (SSRIs)

In most cases, the first medication you'll be offered will be a type of antidepressant called a selective serotonin reuptake inhibitor (SSRI).

This type of medication works byincreasing the level of a chemical called serotonin in your brain.

Examples of SSRIs you may be prescribed include:

  • sertraline
  • escitalopram
  • paroxetine

SSRIscan be taken on a long-term basis but, as with all antidepressants, they can take several weeks to start working.

You'll usually be started on a low dose, which may be gradually increased as your body adjusts to the medication.

Common side effects of SSRIs include:

  • feeling agitated
  • feeling or beingsick
  • indigestion
  • diarrhoeaorconstipation
  • loss of appetiteand weight loss
  • dizziness
  • blurred vision
  • dry mouth
  • excessive sweating
  • headaches
  • problems sleeping (insomnia) or drowsiness
  • low sex drive
  • difficulty achieving org*sm during sex or masturbation
  • in men, difficulty obtaining or maintaining an erection (erectile dysfunction)

These side effects should improve over time, although some may be related to your underlying condition.

Serotonin and noradrenaline reuptake inhibitors (SNRIs)

If SSRIs don't help ease your anxiety, you may be prescribed a different type of antidepressant known asaserotonin and noradrenaline reuptake inhibitor (SNRI).

This type of medication increases the amount of serotonin and noradrenaline in your brain.

Examples of SNRIs you may be prescribed include:

  • venlafaxine
  • duloxetine

Common side effects ofSNRIsinclude:

  • feeling sick
  • headaches
  • drowsiness
  • dizziness
  • dry mouth
  • constipation
  • insomnia
  • sweating
  • sexual problems, such as low sex drive or difficulty getting an erection

SNRIs can also increase your blood pressure, so your blood pressure will be monitored regularly during treatment.

As with SSRIs, some of the side effects (such as feeling sick, an upset stomach, problems sleeping and feeling agitated or more anxious) are more common in the first 1 or 2 weeks of treatment, but these usually settle as your body adjusts to the medication.

Stopping antidepressants

If your medication is not helping after about 2 months of treatment or it's causing unpleasant side effects, your GP may prescribe an alternative medication.

When you and your GP decide it's appropriate for you to stop taking your medication, you'll normally have your dose slowly reduced over the course of a few weeks to reduce the risk of withdrawal effects.

Never stop taking your medication unless your GP specifically advises you to.

Pregabalin

If SSRIs and SNRIs aren't suitable for you, you may be offered pregabalin.

This is a medication known as an anticonvulsant, which is used to treat conditions such as epilepsy, but it's also been found to be beneficial in treating anxiety.

Side effects of pregabalin can include:

  • drowsiness
  • dizziness
  • increased appetite and weight gain
  • blurred vision
  • headaches
  • dry mouth
  • vertigo

Benzodiazepines

Benzodiazepines are a type of sedative that may sometimes be used as a short-term treatment during a particularly severe period of anxiety.

This is because theyhelp ease the symptoms within 30 to 90 minutes of taking the medication.

If you're prescribed a benzodiazepine,it'll usually bediazepam.

Although benzodiazepines are very effective in treating the symptoms of anxiety, they can't be used for long periods.

This is because they can become addictive if used for longer than 4 weeks. Benzodiazepines also start to lose their effectiveness after this time.

For these reasons, you won't usuallybe prescribed benzodiazepines for any longer than 2 to 4 weeks at a time.

Side effects of benzodiazepines can include:

  • drowsiness
  • difficulty concentrating
  • headaches
  • vertigo
  • an uncontrollable shake or tremble in part of the body (tremor)
  • low sex drive

As drowsiness is a particularly common side effect of benzodiazepines, your ability to drive or operate machinery may be affected by taking this medication.

You should avoid these activities during treatment.

You should also never drink alcohol or use opiate drugs when taking benzodiazepine as doing so can be dangerous.

Referral toa specialist

If you have tried the treatments mentioned above and have significant symptoms of GAD, you may want to discuss with your GP whether you should be referred to a mental health specialist.

A referral will work differently in different areas of the UK, but you'll usually be referred to your community mental health team.

These teams include a range of specialists, including:

  • psychiatrists
  • psychiatric nurses
  • clinical psychologists
  • occupational therapists
  • social workers

An appropriate mental health specialist from your local team will carry out an overall reassessment of your condition.

They'll ask you about your previous treatment and how effective you found it.

They may also ask about things in your life that may be affecting your condition, or how much support you get from family and friends.

Your specialist will then be able to devise a treatment plan for you, which will aim to treat your symptoms.

As part of this plan, you may be offered a treatment you haven't tried before, which might bepsychological treatments or medication.

Alternatively, you may be offered a combination of a psychological treatment with a medication, or a combination of 2 different medications.

Treatment - Generalised anxiety disorder in adults (2024)

FAQs

What is the most effective treatment for generalized anxiety disorder? ›

CBT is one of the most effective treatments for GAD. There are several ways you may be offered self-help and CBT: you work through a CBT workbook or computer course in your own time. you work through a CBT workbook or computer course with the support of a therapist who you see every 1 or 2 weeks.

How do you calm down generalized anxiety? ›

Stress management techniques, such as exercise, mindfulness, and meditation, also can reduce anxiety symptoms and enhance the effects of psychotherapy. You can learn more about how these techniques benefit your treatment by talking with a health care provider.

Can I recover from GAD? ›

The prognosis (outlook) for generalized anxiety disorder can vary depending on how severe it is. In some cases, GAD is long-term (chronic) and difficult to treat. However, most people experience improvement in their symptoms with medicine and/or talk therapy.

What is the first line treatment for GAD? ›

Antidepressants, including medications in the selective serotonin reuptake inhibitor (SSRI) and serotonin and norepinephrine reuptake inhibitor (SNRI) classes, are the first line medication treatments.

What is the 3-3-3 rule for anxiety? ›

The 3-3-3 rule is a mindfulness technique that's simple enough for young children. It asks them to name three things they can see, identify three sounds they can hear, and move three different parts of their bodies.

What is the new treatment for generalized anxiety disorder? ›

The US Food and Drug Administration (FDA) has granted breakthrough designation to an LSD-based treatment for generalized anxiety disorder (GAD) based on promising topline data from a phase 2b clinical trial. Mind Medicine (MindMed) Inc is developing the treatment — MM120 (lysergide d-tartrate).

What triggers GAD? ›

The exact cause of GAD is not fully understood, although it's likely that a combination of several factors plays a role. Research has suggested that these may include: the genes you inherit from your parents. having a history of stressful or traumatic experiences, such as domestic violence, child abuse or bullying.

What happens if GAD is left untreated? ›

GAD may result in significant academic, social, and familial impairment. If left untreated, the disorder may be chronic and predicative of adulthood anxiety and depression. However, early identification and effective management can help reduce the severity of symptoms.

Is GAD considered a severe mental illness? ›

Yes; generalized anxiety disorder (GAD) is a serious mental illness that is listed in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5).

What is the gold standard treatment for GAD? ›

Thus, interventions targeting GAD and worry are important and further justify treatment in a variety of clinical settings given the high rate of comorbidity. Cognitive behavioral therapies (CBT) are considered first-line, gold-standard treatments for GAD [7].

What is the first drug of choice for anxiety? ›

Antidepressants are the first-line medications in the treatment of anxiety disorders. Anxiolytics may be used for a brief duration, but only if needed while an antidepressant is being initiated and titrated up. Atypical antipsychotics, mood stabilizers and anticonvulsants are used mainly to augment antidepressants.

What is the most recommended drug for anxiety? ›

SSRIs commonly used to treat chronic anxiety include:
  • Citalopram (Celexa)
  • Escitalopram (Lexapro)
  • Fluoxetine (Prozac)
  • Paroxetine (Paxil)
  • Sertraline (Zoloft)
Jun 29, 2024

Which drug is most rapidly effective for generalized anxiety? ›

Benzodiazepines have a high effective rate for GAD compared to other medication options. 16 They're also fast-acting, providing more immediate anxiety relief.

What is the number one drug for anxiety? ›

SSRIs and SNRIs are often the first-line treatment for anxiety and major depressive disorder. Common SSRI brands are Celexa, Lexapro, Luvox, Paxil, and Zoloft. Common SNRI brands are Pristiq, Cymbalta, and Effexor XR.

What is the most successful treatment for anxiety? ›

Cognitive behaviour therapy (CBT)

Research shows that CBT is the most effective treatment for anxiety, and for preventing future anxiety.

What's the best anxiety medication with the least side effects? ›

Here are the pros and cons of four SSRIs that stand out from the crowd when it comes to having fewer side effects.
  • Celexa. Overall, Celexa seems to be one of the best-tolerated SSRIs for many people. ...
  • Lexapro. Lexapro is closely related to Celexa. ...
  • Prozac. Prozac causes less weight gain than other SSRIs. ...
  • Zoloft.

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